Introduction to Genomics

Introduction to Genomics Course Description:
The Introduction to Genomics course is dedicated to the subject of genomic data and the use of Next Generation Sequencing as a tool to analyze and understand the information contained within a genome. DNA has a double-stranded structure giving it a stable and therefore suitable molecular structure for information storage. The mechanism of DNA replication and the transcription of expressed genes depend on the code contained within a DNA molecule. Changes in a genomic sequence can have dramatic consequences on the resulting protein generated when a gene is expressed. In this review, we will be covering topics that include commonly studied DNA variation (substitutions, insertions and deletions) and looking at a few examples of how DNA variation can affect health, disease and treatment (reference). At the end, you will have the option to apply the acquired understanding to one of our prepared projects or a project of your own.
In a subsequent course, Genomics 1, we will also discuss the analytical challenges associated with data preparation, analysis and interpretation of sequencing results.
Questions we will try to answer:
- What is DNA variation and what types of variation are there?
- What DNA elements are being studied for variation?
- What types of genomic information exist and can be analyzed?
Terms you will learn about:
- Genetics
- Genomics
- Base pair
- Point Mutation (insertion, deletion, and substitution)
- Translocation
- Inversion
- Mutation
- Variant calling
- Germline mutation
- Somatic mutation
Course Features
- Lectures 7
- Quizzes 2
- Duration 50 hours
- Skill level All levels
- Language English
- Students 1443
- Certificate Yes
- Assessments Yes
-
DNA structure and variants
-
Types of Genome Sequencing
-
nancynzelu
Confused
I enjoyed the course but i'm kind of disappointed. I passed the 2nd quiz after 3 trials (lots of confusing words, more of english exam), I am yet to see an update in my points. Please help resolve this
-
kshimaelyx
DNA Basics and Sequencing
The course is well planned. It has covered a lot and has helped refreshed my understand this aspect; particularly the sequencing techniques with their applications. However, some explanations were not concise perhaps due to shift in wordings. For instance, I found it difficult understanding aspect on GRCh38 vs GRCh 37 as well as how to measure the length of base pairs. This had made getting through the quizzes very tough. It will suggest inclusion of video/s for course for more demonstrations.
-
oluwasanmiadetutu
Course
The course content is explanatory for beginners and it offers great insights into the field of genomics.
-
adeloyefave
Course
I would like two retake this course again, pls help me out as i cant find the means to
-
Abuaisha15
Abu Aishatu 15
This course is really precise and full of information. It's really an introduction that even one who has no idea of cell biology could come out with something. Good work
19 Comments
Excellent course !!
Well Designed for a beginner
Explicit explanation of the basics of GENOMICS…….
Perfect to brush up all the basics of Genomics
Enjoyed the content very much. Unfortunately, I had trouble getting through the quizzes because of the shifty wording. However, I am grateful for learning about the different sequencing techniques available along with their pros and cons.
Great content. Detailed and interesting
How do i get the certificate please?
many thanks
After you would have clicked on finish, you will be redirected to the course curriculum. That’s where you will find the “certificate” option highlighted in green.
After several attempts I could not get through the quiz yet I learned a lot and understand virtually everything. Perfectly designed.
Hi I can not access the certificate for this course.. can you please send me it to my email? Thanks!
you should be able to see your certificates under your profile: https://edu.t-bio.info/members/yana-gupta/courses/certificates/
Good course for beginners and experts alike
It’s a beginner-friendly course content. Well detailed and understood
Pls am having issues obtaining my certificate, and I think the answers for the quizzes should be reviewed. Thank you.
Thank you for your suggestions – your certificate should be under the profile/courses and if you have quiz change suggestions, please email: support@pine.bio
Highly comprehensive!
Great way to understand genomics!
Well structured and organized course. Perfect for beginners and professionals. Detailed materials also. Thank you pinebio.
The wordings and answers to the quizzes should be reviewed.
thank you for the suggestion, we will review!