Introduction to Genomics
Introduction to Genomics Course Description:
The Introduction to Genomics course is dedicated to the subject of genomic data and the use of Next Generation Sequencing as a tool to analyze and understand the information contained within a genome. DNA has a double-stranded structure giving it a stable and therefore suitable molecular structure for information storage. The mechanism of DNA replication and the transcription of expressed genes depend on the code contained within a DNA molecule. Changes in a genomic sequence can have dramatic consequences on the resulting protein generated when a gene is expressed. In this review, we will be covering topics that include commonly studied DNA variation (substitutions, insertions and deletions) and looking at a few examples of how DNA variation can affect health, disease and treatment (reference). At the end, you will have the option to apply the acquired understanding to one of our prepared projects or a project of your own.
In a subsequent course, Genomics 1, we will also discuss the analytical challenges associated with data preparation, analysis and interpretation of sequencing results.
Questions we will try to answer:
- What is DNA variation and what types of variation are there?
- What DNA elements are being studied for variation?
- What types of genomic information exist and can be analyzed?
Terms you will learn about:
- Base pair
- Point Mutation (insertion, deletion, and substitution)
- Variant calling
- Germline mutation
- Somatic mutation
- Lectures 7
- Quizzes 2
- Duration 50 hours
- Skill level All levels
- Language English
- Students 574
- Certificate Yes
- Assessments Yes
DNA structure and variants
Types of Genome Sequencing
This'll be your quickest 500 points, I promise!
Introduction to Genomics is one of those relatively lighter modules and it lays out a very elementary view of what genome is. It discusses the essential structural & functional features of the DNA along with an overview of different approaches adopted in sequencing (WES, WGS, etc)
ABCs of Genomics
This course provides the fundamentals of Genomics. The course has explained every genomic related terms in an efficient manner. I had a very pleasing experience while going through the course.
The module touched the base on what a gene is and sequencing techniques to read a DNA. Good Intro
Perfect Introduction to Genomics concept!
Introduction to Genomics is a very basic and essential course which lucidly lays down the basic details of the most valuable unit of life – The DNA. It deals with the various types of sequencing techniques like – Targeted sequencing, Exome sequencing and Whole Genome sequencing. It is a wonderful experience to learn about them and also correctly differentiate between them.
This module briefs very well on what Genome and Genomics is, and how we do studies related to it.