Introduction to Metagenomics
Introduction to Metagenomics Course Overview
Metagenomics is the study of genetic information shared by microbiological communities. Through sequencing technology (Next Generation Sequencing or NGS) it is now possible to align, map and annotate genomes to a reference database in order to begin to understand factors that regulate behaviors and interactions among these microbial communities. The information we collect studying bacteria, archaea, microbial eukaryotes and viruses found in these habitats provide examples of how the collective and often complex genotypes sustain life within these environmental communities.
The genetic make up of organisms within a microbiome suggests that complex communities of microorganisms collectively influence Biological stability of an ecosystem. The microbes living around, on and within the human body (outnumbering the cells of the human body by 10 to 1) are also widely distributed, complex and dynamic communities that have a profound influence on human health, disease and physiology (see reference). These communities also surround plant roots and can help fight off harmful bacteria and create a layer the plant roots rely on to grow and extract useful minerals from the soil. Our understanding of the microbiome function and ways to analyze these communities can help us treat disease, improve human health and wellbeing and even identify ways to improve or protect crop production.
In this course, you will be familiarized with the way microbiomes influence their hosts and compose a unique community we can study using next generation sequencing. Introduction to Metagenomics will describe the process of sequencing of the bacterial 16S genome. Using the sequential processing of a metagenomics analysis pipeline, you will be able to make comparisons between samples and a reference database. After this course, we recommend to complete Metagenomics 1.
- Lectures 10
- Quizzes 2
- Duration 50 hours
- Skill level All levels
- Language English
- Students 482
- Certificate Yes
- Assessments Yes
Introduction to Metagenomics
The Microbiome and Human Health
Alice in Wonderland!
The context of the title being; we are Alice and the microbiome is Wonderland! This introductory course runs you through the concepts of the symbiotic relationship between microbiota and it's environment which can be human/nature. Again, like the previous courses the lectures are coupled with two quizzes and helps you absorb the essential facts. You will also find the lectures loaded with literature references that you can further explore to get well versed. Introduction to Metagenomics acts as a good platform to go into Metagenomics-1 where the NGS data analysis is dealt with.
Introduction to Metagenomics Course
The course offers a well designed introduction to metagenomics. Good theoretical background for anyone starting to learn about this type of data and various ways it could be used.