Neurology

Cancer is an important challenge for which personalized molecular medicine shows great promise. Recent advances in immunotherapy and genetic testing have been proposed to help transform care from one-size-fits-all to a highly specialized range of options that could be adapted to fit an individual’s molecular features. However, we are still far from understanding and navigating cancer. In fact, many promising research projects that reveal new targets and promising strategies that work on animal models fail in clinical trials. While generating data has been increasingly accessible, the challenge is now in integration and extracting insights from this data. A multi-omics approach based on big data analyses could lead to substantial advances in cancer treatment.

Real Projects from High Impact Publications

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Cutting Edge Research

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From Basic Biology to Application

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Neurology

Neuroscience research methods strongly benefit from usage of biomedical big data. Recent research has focused on employing novel research methods into elucidating the different genetic factors that underlie many neurological diseases. It is estimated that 18.5% of Americans have some type of mental illness every year. Additionally, Parkinson’s and Alzheimer’s Disease have some of the highest rates of death for elderly individuals. Traditional research methods have failed to properly assess the different components of the disease, treatments and underlying factors. By utilizing data sets, more information can be produced to generate a holistic picture of these diseases.

To promote students and professionals understanding of how big data is utilized in Neuroscience, Pine Biotech as well as our academic collaborators, have prepared curricula and projects that focus on different aspects of diseases in Neuroscience. Students will utilize adapted data sets from published work and will learn hands-on how to assess and analysis data pertaining to Neuroscience. The course will cover these following areas of Neuroscience:

  • Molecular indicators of neuroscience via variation in single nucleotide variants (SNV’s) or small indels, as well and CNV’s
  • Different regulatory elements involved in the pathogenesis Autism, schizophrenia and Parkinson’s
  • Early markers of developmental disorders
  • The effects of adverse effects/environmental factors that lead to development of neurological diseases
  • How big data is being utilized in the clinical environment to better target these diseases
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Courses

Course 1

Transcriptomics 1

Molecular biology is a vast and eclectic field, composed of many branches and subdisciplines. Molecular biologists study a broad spectrum of topics relating to the molecular regulation of cell biology, from DNA and RNA, to protein expression and protein-protein interactions. A dominant theme in molecular biology is how variation in nucleic acids (genotype) affects the biology of organisms (phenotype). The 2 main types of nucleic acid variation are:

  • gene variation at the level of DNA (genomics)
  • variation in gene expression (transcriptomics)
Commitment : 1-4 hours/week
Subtitles : English, French, Chinese (Simplified), Greek, Italian, Portuguese (Brazilian), Vietnamese, Russian, Turkish, Hebrew

Course 2

Transcriptomics 2

Molecular biology is a vast and eclectic field, composed of many branches and subdisciplines. Molecular biologists study a broad spectrum of topics relating to the molecular regulation of cell biology, from DNA and RNA, to protein expression and protein-protein interactions. A dominant theme in molecular biology is how variation in nucleic acids (genotype) affects the biology of organisms (phenotype). The 2 main types of nucleic acid variation are:

  • gene variation at the level of DNA (genomics)
  • variation in gene expression (transcriptomics)
Commitment : 1-4 hours/week
Subtitles : English, French, Chinese (Simplified), Greek, Italian, Portuguese (Brazilian), Vietnamese, Russian, Turkish, Hebrew

Course 3

Metagenomics 1

Molecular biology is a vast and eclectic field, composed of many branches and subdisciplines. Molecular biologists study a broad spectrum of topics relating to the molecular regulation of cell biology, from DNA and RNA, to protein expression and protein-protein interactions. A dominant theme in molecular biology is how variation in nucleic acids (genotype) affects the biology of organisms (phenotype). The 2 main types of nucleic acid variation are:

  • gene variation at the level of DNA (genomics)
  • variation in gene expression (transcriptomics)
Commitment : 1-4 hours/week
Subtitles : English, French, Chinese (Simplified), Greek, Italian, Portuguese (Brazilian), Vietnamese, Russian, Turkish, Hebrew

Projects

Cell lines to study cancer subgroups

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Macrophages

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PDX study of tumor-stroma interaction

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TCGA triple negative breast cancer

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Certificate

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Pilots and Advisors

Dr. Kasthuri Kannan

(NYU)

Dr. Lucio Miele

(LSU)

Dr. Dario Ghesi

(UNO)

Project Team

Dr. Ronald Ferucci

Julia Panov

Sahil Sethi

FAQ’s

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Fusce et pretium purus. Sed eu tincidunt ipsum, et ullamcorper erat. Proin congue consect sdfetur dui et convallis. Mauris accu msan lectus in diam pretium, ac aliquet tellus Suspendisse vel lectus eu magna commodo aliquam. Nunc nec lorem orci. Pelle ntesque facilisis lacus ac velit imperdiet, sit amet accumsan ex pellentesque. Nullam malesuada ligula vel magna vulputate cons equat. Fusce nec rhoncus sem, a varius risus. Donec tristique rhoncus metus, ut venenatis lacus porta sit amet. Nulla facilisi. Sed et magna mauris. Aliquam interdum eu dolor quis ultricies.

Fusce et pretium purus. Sed eu tincidunt ipsum, et ullamcorper erat. Proin congue consect sdfetur dui et convallis. Mauris accu msan lectus in diam pretium, ac aliquet tellus Suspendisse vel lectus eu magna commodo aliquam. Nunc nec lorem orci. Pelle ntesque facilisis lacus ac velit imperdiet, sit amet accumsan ex pellentesque. Nullam malesuada ligula vel magna vulputate cons equat. Fusce nec rhoncus sem, a varius risus. Donec tristique rhoncus metus, ut venenatis lacus porta sit amet. Nulla facilisi. Sed et magna mauris. Aliquam interdum eu dolor quis ultricies.

Fusce et pretium purus. Sed eu tincidunt ipsum, et ullamcorper erat. Proin congue consect sdfetur dui et convallis. Mauris accu msan lectus in diam pretium, ac aliquet tellus Suspendisse vel lectus eu magna commodo aliquam. Nunc nec lorem orci. Pelle ntesque facilisis lacus ac velit imperdiet, sit amet accumsan ex pellentesque. Nullam malesuada ligula vel magna vulputate cons equat. Fusce nec rhoncus sem, a varius risus. Donec tristique rhoncus metus, ut venenatis lacus porta sit amet. Nulla facilisi. Sed et magna mauris. Aliquam interdum eu dolor quis ultricies.

Fusce et pretium purus. Sed eu tincidunt ipsum, et ullamcorper erat. Proin congue consect sdfetur dui et convallis. Mauris accu msan lectus in diam pretium, ac aliquet tellus Suspendisse vel lectus eu magna commodo aliquam. Nunc nec lorem orci. Pelle ntesque facilisis lacus ac velit imperdiet, sit amet accumsan ex pellentesque. Nullam malesuada ligula vel magna vulputate cons equat. Fusce nec rhoncus sem, a varius risus. Donec tristique rhoncus metus, ut venenatis lacus porta sit amet. Nulla facilisi. Sed et magna mauris. Aliquam interdum eu dolor quis ultricies.

Fusce et pretium purus. Sed eu tincidunt ipsum, et ullamcorper erat. Proin congue consect sdfetur dui et convallis. Mauris accu msan lectus in diam pretium, ac aliquet tellus Suspendisse vel lectus eu magna commodo aliquam. Nunc nec lorem orci. Pelle ntesque facilisis lacus ac velit imperdiet, sit amet accumsan ex pellentesque. Nullam malesuada ligula vel magna vulputate cons equat. Fusce nec rhoncus sem, a varius risus. Donec tristique rhoncus metus, ut venenatis lacus porta sit amet. Nulla facilisi. Sed et magna mauris. Aliquam interdum eu dolor quis ultricies.