Bioinformatics for Infectious Diseases is a program developed in collaboration with Noguchi Memorial Institute for Medical Research (NMIMR), Ghana’s leading biomedical research institute at the University of Ghana. The program is designed to introduce students, clinicians, and researchers to the role and the applications of bioinformatics to the study of pathogenic microorganisms and their interaction with the host and vectors. The program will be led by Omics Logic mentors who have considerable expertise with virology, immunology and bioinformatics. A group of research participants from the University of Ghana will be led by their Principal Investigator: Dr. Anita Ghansah (firstname.lastname@example.org) and Dr. Bright Abu. and other researchers from the Noguchi Memorial Research Institute and Rhodes University (SA).
Bioinformatics analysis of public domain data
First- and Second- Generation Sequencing Data types, approaches and resulting data types
Pathogen Genome Analysis using examples of viral, bacterial and parasite pathogens
Pairwise and Multiple Sequence Alignment
Phylogenetic Tree Reconstruction, rate of mutation and association with time
Working with Protein Structures to map variants, examine properties and match structures
RNA-Seq Data Analysis to study immune response to infection and compare treatment effects
Rapid literature review for data, methods and sample meta-data organization
Data visualization, structure, data types; Exploratory Analysis: PCA, PCoA, NMDS
Malaria: Vaccines, structures, drug-resistance genes and proteins COVID: evolution, vaccine design, drug response
Student presentations and feedback (Webinar open to general public)
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